A QUANTITATIVE STUDY OF THE SCARLET FEVER TOXIN-ANTITOXIN FLOCCULATION REACTION
نویسندگان
چکیده
منابع مشابه
A Quantitative Study of the Scarlet Fever Toxin-antitoxin Flocculation Reaction
1. Highly purified scarlet fever toxin has been prepared from culture filtrates of two scarlatinal strains (NY5 and 594B) of hemolytic streptococcus grown on a medium of defined composition. 2. The flocculation reaction of Rane and Wyman has been studied quantitatively and has been shown specific for scarlet fever toxin and antitoxin. 3. Scarlet fever toxin from strains NY5 and 594B are quantit...
متن کاملThe Nature of the Toxin-antitoxin Flocculation Phenomenon
1. Animals immunized with the formalinized filtrates of young toxic cultures of B. botulinus produce an antitoxic serum poor in precipitins. 2. Animals immunized with the formalinized filtrates of old and partly autolyzed toxic cultures produce an antitoxic serum containing precipitins. 3. Animals immunized with toxin-free autolyzed bacteria produce a serum free from antitoxin but rich in speci...
متن کاملToxin-antitoxin Reaction without Neutralization
1. Collodion particles adsorb diphtheria or tetanus or botulinus toxins. These toxins are retained on the particles when washed but are at least in part released in the animal. 2. The adsorbed toxins are neutralized by adsorption of the corresponding antitoxins but are unaffected by other serums. 3. When collodion particles are treated first with tetanus antitoxin, then with diphtheria toxin, t...
متن کاملThe Routine Preparation of Scarlet-fever Toxin of High Value
A NUMBER of attempts have been made in recent years to improve the quality of scarlet fever toxin, of which the most noteworthy is that of Hooker et al. (1933), who by a special technique obtained toxin with a value of 500,000 skin test doses per c.c. For some time past, however, the routine toxins prepared in this laboratory have been of considerably greater potency than those described by the...
متن کاملThe pyrogenic effect of scarlet fever toxin. IV. Pyrogenicity of strain C 203 U filtrate: comparison with some basic characteristics of the known types of scarlet fever toxin.
The pyrogenic activity of scarlet fever toxin has been described a number of times. The "classic" toxin, prepared from the Dochez NY 5 strain, was found to have a double specificity, designed by Hooker and Follensby as "A" and "B".1 More recently, Watson has analyzed the antigenic components of this toxin and found a third type, which he has denoted "C"1.2 In working with a mutant strain of str...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1941
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.74.6.545